Physiology & Pathophysiology, Ph.D.
Physiology & Pathophysiology
Head: Dr. Peter Cattini
Grad Chair: Dr. Brent Fedirchuk
Campus Address/General Office: 433 Basic Medical Sciences Building
Telephone: 204-789-3694
Fax: 204-789-3934
Email Address: peter.cattini@umanitoba.ca
Website: umanitoba.ca/faculties/health_sciences/medicine/units/physiology/
Academic Staff: Please refer to the Physiology & Pathophysiology website for current staff listing.
Physiology & Pathophysiology Program Information
The department offers graduate programs leading to the Master of Science and Doctor of Philosophy degrees.
Admission Information
Admission to the Faculty of Graduate Studies
Application and Admission Procedures are found in the Academic Guide.
Admission requirements for doctoral students are found in the Doctor of Philosophy General Regulations section of the Guide.
Physiology & Pathophysiology Ph.D. Admission Requirements
Admission requirements are those of the Faculty of Graduate Studies.
Application Information
Students should complete and submit their online application with supporting documentation by the date indicated on the Physiology & Pathophysiology Ph.D. program of study page.
Degree Requirements
Students who have obtained a Master's degree (including 9 or more credit hours of coursework at the 7000 level) will be required to take a minimum of an additional 9 credit hours to meet the requirements of the Ph.D. For students transferring from the M.Sc. program into the Ph.D., a minimum of 6 credit hours are required to meet the requirements of the Ph.D. beyond the 9 credit hours obtained under the M.Sc. program.
Additional courses that are deemed appropriate by the Student's Advisory Committee may be taken with the approval of the Department of Physiology & Pathophysiology Graduate Program Committee, up to a maximum of 24 credit hours (4 FCE). Note: a 0.5 FCE corresponds to a course that runs for a full term.
Expected Time to Graduate: 4 years
Progression Chart
| Year 1 | Hours | |
|---|---|---|
| GRAD 7300 | Research Integrity Tutorial | 0 |
| GRAD 7500 | Academic Integrity Tutorial | 0 |
| Coursework 1 | 9 | |
| Hours | 9 | |
| Years 2-5 | ||
| GRAD 8000 | Doctoral Thesis | 0 |
| Hours | 0 | |
| Total Hours | 9 | |
| 1 | Student & Advisor decide on courses. |
Registration Information
Students should familiarize themselves with the Faculty of Graduate Studies ‘GRAD’ courses applicable to their program. If you have questions about which GRAD course(s) to register in, please consult your home department/unit.
Prior to registration, all new and returning students must meet with their advisor to determine their program of study. All course additions and withdrawals (registration revisions) must be approved in the same manner.
Not all courses are offered every year and some courses will be held only with a minimum enrolment.
Regulations
Students must meet the requirements as outlined in both Supplementary Regulation and BFAR documents as approved by Senate.
Supplementary Regulations
Individual units may require specific requirements above and beyond those of the Faculty of Graduate Studies, and students should consult unit supplementary regulations for these specific regulations.
Bona Fide Academic Requirements (BFAR)
Bona Fide Academic Requirements (BFAR) represent the core academic requirements a graduate student must acquire in order to gain, and demonstrate acquisition of, essential knowledge and skills.
All students must successfully complete:
- GRAD 7300 prior to applying to any ethics boards which are appropriate to the student’s research or within the student’s first year, whichever comes first; and
- GRAD 7500 within the first term of registration;
unless these courses have been completed previously, as per Mandatory Academic Integrity Course and Mandatory Research Integrity Online Course.
Students must also meet additional BFAR that may be specified for their program.
General Regulations
All students must:
- maintain a minimum degree grade point average of 3.0 with no grade below C+,
- meet the minimum and not exceed the maximum course requirements, and
- meet the minimum and not exceed the maximum time requirements (in terms of time in program and lapse or expiration of credit of courses).
Note: Physiology & Pathophysiology requires a higher minimum course grade. Students are required to maintain a B (3.0) in all course work.
Courses
Tutorial course covering recent contributions in an area of physiology related to a student's research interests.
Seminar and reading course on physiology of particular systems.
Tutorial and reading course on cardiac physiology; emphasis on the energetics of cardiac contraction and its relationship to ultrastructural and biochemical properties of the heart.
Lectures and seminars on physiology of blood vessels including hemodynamics, rheology of blood, and the function and structure of smooth muscle.
Special topics in endocrine and metabolic physiology emphasizing current concepts.
A seminar course on advanced topics in endocrine and metabolic physiology and diseases. The course focuses on developing skills required to present and critique research data on endocrine and metabolic physiology & pathophysiology.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: PHGY 7256 or consent of course coordinator.
Advances in selected areas of physiology, research proposals related to the student's area of interest, procedures for grant writing and refereeing grant proposals, evaluation of citations and impact factors.
Seminars on research presentations by staff and senior students in physiology.
Tutorial course: Function of various organs in the light of current concepts regarding structure and function at the molecular and cellular level.
Lecture, readings, and student-directed discussion course dealing with fundamental biophysical processes and function of major respiratory organ systems (including membrane transport and muscle contraction in respiratory physiology), illustrated with pathophysiological structures and function, and their relationship to disease. The course will also examine current therapeutic approaches and active areas of research interest.
Lecture, readings, and student-directed discussion course dealing with fundamental biophysical processes and function of major cardiovascular organ systems, illustrated with pathophysiological structures and function, and their relationship to disease. The course will also examine current therapeutic approaches and active areas of research interest.
Lecture, readings, and student-directed discussion course dealing with fundamental biophysical processes and function of major endocrine (including reproductive) organ systems, illustrated with pathophysiological structures and function, and their relationship to disease. The course will also examine current therapeutic approaches and active areas of research interest.
Lecture, readings, and student0directed discussion course dealing with fundamental biophysical processes and function of major neurophysiology organ systems, illustrated with pathophysiological structures and function, and their relationship to disease. The course will also examine current therapeutic approaches and active areas of research interest.
Seminar, readings and lecture course covering original research papers leading to the most significant advances in the neurological sciences. Emphasis is placed on student comprehension of major research directions in the broad field of neurological sciences.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: PHGY 7240 or equivalent and consent of instructor.
A lecture and seminar course dealing with the physiology and biophysics of skeletal and cardiac muscle.
A lecture and seminar course dealing with the physiology of the airways in the intact animal and with the role of smooth muscle in controlling airway function. The fundamental properties of airway smooth muscle in controlling airway function will be emphasized.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: PHGY 7240 or equivalent and consent of instructor.
A lecture and seminar course on advances in molecular and cellular aspects of endocrinology and other systems. The course is taught by members of the Gene Technology Group and topics will reflect current research interests. These include the roles of hormones/growth factors in cancer, growth and development, and reproduction, and the regulation of hormone gene families. This course is designed for individuals with knowledge in the areas of molecular and/or cell biology.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: consent of instructor.
Lectures on basic principles of electricity and electronics of particular application to electrophysiology.
Lectures on the application of principles of electricity and electronics to electrophysiology.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: PHGY 7310.
A lecture and seminar course dealing with the biophysics, electrophysiology, pharmacology and biochemistry of the smooth muscle in the major organ systems.
A comprehensive lecture and seminar course on the electrical activity of the cardiovascular system. The fundamental electrical properties of cardiac and vascular muscle cell membranes, currents and channels as studied by intracellular microelectrodes, voltage clamp and patch clamp techniques will be stressed.
A comprehensive lecture course on disease in the cardiovascular system. Topics to be covered include methods of analysis of cardiac viability, heart failure, arrhythmias, heart diseases (congenital, valvular, pericardial, cardiomyopathy), hypertension, stroke, atherosclerosis and myocardial infarction.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: PHGY 7240.
This is a comprehensive seminar-based course dealing with recent advances in cardiovascular research given by local fellows and prominent scientists. Students are expected to participate in the series and present their own research data seminar. This course will enable the trainees to learn how to prepare research seminars, handle question/answer sessions after a seminar and prepare a formal report.
This course introduces the principles of molecular biology and their application to the cardiovascular system in health and disease, with a focus on gene regulation, cardiac development and the use of transgenic models. The course comprises lectures and student self-directed learning assignments.
PR/CR: A minimum grade of C is required unless otherwise indicated.
Prerequisite: PHGY 7254 or permission of instructor.
A comprehensive lecture course on morphology, biochemical composition and function of the cardiac and smooth muscle cell, with particular emphasis on developmental and injury-related issues. Topics include the description of various cardiac cells and their immediate extracellular environment, intercellular communication, cardiac development, control of cell cycle, hyperplasia and hypertrophy, cardiac growth factors, mechanism of injury and cell death, regeneration, heat shock proteins and cardioprotection.
Advanced course detailing new frontiers in the application of gene therapy and technological protocols currently utilized in treating cardiovascular diseases such as cardiomyopathy, hypertension, congenital birth defects and restenosis.
This course provides current concepts in vascular biology at the molecular level as well as the pathogenesis and treatment of vascular diseases for the purpose of graduate studies. Students may also learn up-to-date techniques in research of vascular cell biology and the diagnosis of vascular diseases through laboratory demonstrations.